CREM anticorps

N° du produit ABIN2461049

Détail du produit anti-CREM anticorps

Antigène: CREM (CAMP Responsive Element Modulator (CREM))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CREM est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CREM.

Information d'application

Indications d'application: CREM antibody can be used for detection of CREM by ELISA at 1:1562500. CREM antibody can be used for detection of CREM by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CREM antibody at -20 °C.

Détails sur CREM

Antigène: CREM (CAMP Responsive Element Modulator (CREM))

Autre désignation: CREM (CREM Produits)

Synonymes: anticorps CREM, anticorps ICER, anticorps CREM-2, anticorps hCREM-2, anticorps ICERI, anticorps Icer, anticorps cAMP responsive element modulator, anticorps CREM, anticorps Crem

Sujet: CREM is a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription.

Poids moléculaire: 13 kDa

ID gène: 1390

NCBI Accession: NP_874386

UniProt: O75519

Pathways: Retinoic Acid Receptor Signaling Pathway