KCNN3 anticorps

N° du produit ABIN2461100

Détail du produit anti-KCNN3 anticorps

Antigène: KCNN3 (Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))

Reactivité: Humain, Rat, Souris, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNN3 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KCNN3.

Information d'application

Indications d'application: KCNN3 antibody can be used for detection of KCNN3 by ELISA at 1:62500. KCNN3 antibody can be used for detection of KCNN3 by western blot at 2 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store KCNN3 antibody at -20 °C.

Détails sur KCNN3

Antigène: KCNN3 (Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))

Autre désignation: KCNN3 (KCNN3 Produits)

Synonymes: anticorps KCa2.3, anticorps SK3, anticorps SKCA3, anticorps hSK3, anticorps potassium calcium-activated channel subfamily N member 3, anticorps potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3, anticorps Kcnn3, anticorps KCNN3

Sujet: Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. KCNN3, a member of the KCNN family of potassium channel genes, encodes a protein that is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits.

Poids moléculaire: 81 kDa, 48 kDa

ID gène: 3782

NCBI Accession: NP_002240

UniProt: Q9UGI6