TRIM21 anticorps

N° du produit ABIN2461681

Cet anticorps Lapin Polyclonal détecte spécifiquement TRIM21 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour TRIM21 anticorps (ABIN2461681)

Antigène: TRIM21 (Tripartite Motif Containing 21 (TRIM21))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIM21 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TRIM21 anticorps

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TRIM21.

Information d'application

Indications d'application: TRIM21 antibody can be used for detection of TRIM21 by ELISA at 1:1562500. TRIM21 antibody can be used for detection of TRIM21 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TRIM21 antibody at -20 °C.

Détails sur TRIM21

Antigène: TRIM21 (Tripartite Motif Containing 21 (TRIM21))

Autre désignation: TRIM21

Sujet: TRIM21 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. TRIM21 is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus.This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Poids moléculaire: 54 kDa

ID gène: 6737

NCBI Accession: NP_003132

UniProt: P19474