SAP18 anticorps

N° du produit ABIN2461767

Cet anticorps anti-SAP18 est un anticorps Lapin Polyclonal détectant SAP18 dans WB et ELISA. Adapté pour Humain, Souris, Rat et Chien.

Aperçu rapide pour SAP18 anticorps (ABIN2461767)

Antigène: SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SAP18 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-SAP18 anticorps

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SAP18.

Information d'application

Indications d'application: SAP18 antibody can be used for detection of SAP18 by ELISA at 1:312500. SAP18 antibody can be used for detection of SAP18 by western blot at 0.125 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SAP18 antibody at -20 °C.

Détails sur SAP18

Antigène: SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))

Autre désignation: SAP18

Sujet: Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. SAP18 is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter.Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter.

Poids moléculaire: 18 kDa

ID gène: 10284

NCBI Accession: NP_005861

UniProt: O00422