MafF anticorps

N° du produit ABIN2461834

Détail du produit anti-MafF anticorps

Antigène: MafF (MAFF) (Transcription Factor MafF (MAFF))

Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Drosophila melanogaster

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MafF est non-conjugé

Application: ELISA, Western Blotting (WB)

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MAFF.

Information d'application

Indications d'application: MAFF antibody can be used for detection of MAFF by ELISA at 1:62500. MAFF antibody can be used for detection of MAFF by western blot at 5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MAFF antibody at -20 °C.

Détails sur MafF

Antigène: MafF (MAFF) (Transcription Factor MafF (MAFF))

Autre désignation: MAFF (MAFF Produits)

Synonymes: anticorps zgc:63868, anticorps MAFF, anticorps U-MAF, anticorps hMafF, anticorps MAF bZIP transcription factor F, anticorps v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F, anticorps v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F S homeolog, anticorps v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian), anticorps Maff, anticorps maff, anticorps MAFF, anticorps maff.S

Sujet: MAFF is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. MAFF can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. MAFF may also be involved in the cellular stress response.The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Two transcript variants encoding the same protein have been found for this gene.

Poids moléculaire: 18 kDa, 18 kDa, 18 kDa, 18 kDa, 18 kDa

ID gène: 23764

NCBI Accession: NP_690617

UniProt: Q9ULX9

Pathways: Myometrial Relaxation and Contraction