ZNF496 anticorps
Aperçu rapide pour ZNF496 anticorps (ABIN2461953)
Antigène
Voir toutes ZNF496 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Antibody is purified by protein A chromatography method.
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Immunogène
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ZNF496.
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Indications d'application
- ZNF496 antibody can be used for detection of ZNF496 by ELISA at 1:62500. ZNF496 antibody can be used for detection of ZNF496 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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Concentration
- 1 mg/mL
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Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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Conseil sur la manipulation
- As with any antibody avoid repeat freeze-thaw cycles.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store ZNF496 antibody at -20 °C.
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- ZNF496 (Zinc Finger Protein 496 (ZNF496))
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Autre désignation
- ZNF496
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Sujet
- ZNF496 contains a SCAN box, a KRAB-A domain, and four consensus C2H2-type zinc fingers preceded by a unique finger derivative, referred to herein as the C2HR motif. The C2HR motif functions to mediate protein-protein interaction with the cysteine-rich (C5HCH) domain of NSD1 in a Zn (II)-dependent fashion, and when tethered to RNA polymerase II promoters, represses transcription in an NSD1-dependent manner. ZNF496 contains a novel type of zinc finger motif that functions as a docking site for NSD1 and is more than just a degenerate evolutionary remnant of a C2H2 motif.
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Poids moléculaire
- 67 kDa
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ID gène
- 84838
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NCBI Accession
- NP_116141
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UniProt
- Q96IT1
Antigène
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