ZNF496 anticorps

N° du produit ABIN2461953

Détail du produit anti-ZNF496 anticorps

Antigène: ZNF496 (Zinc Finger Protein 496 (ZNF496))

Reactivité: Souris, Humain, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZNF496 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ZNF496.

Information d'application

Indications d'application: ZNF496 antibody can be used for detection of ZNF496 by ELISA at 1:62500. ZNF496 antibody can be used for detection of ZNF496 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ZNF496 antibody at -20 °C.

Détails sur ZNF496

Antigène: ZNF496 (Zinc Finger Protein 496 (ZNF496))

Autre désignation: ZNF496 (ZNF496 Produits)

Synonymes: anticorps Zkscan17, anticorps Znf496, anticorps ZNF496, anticorps NIZP1, anticorps ZFP496, anticorps ZKSCAN17, anticorps ZSCAN49, anticorps BC040205, anticorps D130067D09, anticorps Nizp1, anticorps Zfp496, anticorps zinc finger protein 496, anticorps zinc finger with KRAB and SCAN domains 17, anticorps Zfp496, anticorps ZNF496, anticorps Zkscan17

Sujet: ZNF496 contains a SCAN box, a KRAB-A domain, and four consensus C2H2-type zinc fingers preceded by a unique finger derivative, referred to herein as the C2HR motif. The C2HR motif functions to mediate protein-protein interaction with the cysteine-rich (C5HCH) domain of NSD1 in a Zn (II)-dependent fashion, and when tethered to RNA polymerase II promoters, represses transcription in an NSD1-dependent manner. ZNF496 contains a novel type of zinc finger motif that functions as a docking site for NSD1 and is more than just a degenerate evolutionary remnant of a C2H2 motif.

Poids moléculaire: 67 kDa

ID gène: 84838

NCBI Accession: NP_116141

UniProt: Q96IT1