EIF4G2 anticorps
Aperçu rapide pour EIF4G2 anticorps (ABIN2462107)
Antigène
Voir toutes EIF4G2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Purification
- Antibody is purified by peptide affinity chromatography method.
-
Immunogène
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EIF4G2.
-
-
-
-
Indications d'application
- EIF4G2 antibody can be used for detection of EIF4G2 by ELISA at 1:312500. EIF4G2 antibody can be used for detection of EIF4G2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
-
Concentration
- 1 mg/mL
-
Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
-
Conseil sur la manipulation
- As with any antibody avoid repeat freeze-thaw cycles.
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store EIF4G2 antibody at -20 °C.
-
-
- EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))
-
Autre désignation
- EIF4G2
-
Sujet
- Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. EIF4G2 shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3, eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, EIF4G2 functions as a general repressor of translation by forming translationally inactive complexes.
-
Poids moléculaire
- 39 kDa, 98 kDa, 102 kDa
-
ID gène
- 1982
-
UniProt
- P78344
Antigène
-