EXOSC6 anticorps

N° du produit ABIN2462323

Cet anticorps Lapin Polyclonal détecte spécifiquement EXOSC6 dans WB et ELISA. Il présente une réactivité envers Humain, Souris, Rat et Chien.

Aperçu rapide pour EXOSC6 anticorps (ABIN2462323)

Antigène: EXOSC6 (Exosome Component 6 (EXOSC6))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EXOSC6 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-EXOSC6 anticorps

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EXOSC6.

Information d'application

Indications d'application: EXOSC6 antibody can be used for detection of EXOSC6 by ELISA at 1:62500. EXOSC6 antibody can be used for detection of EXOSC6 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store EXOSC6 antibody at -20 °C.

Détails sur EXOSC6

Antigène: EXOSC6 (Exosome Component 6 (EXOSC6))

Autre désignation: EXOSC6

Sujet: EXOSC6 constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly (A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation.This gene product constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly (A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation.

Poids moléculaire: 30 kDa

ID gène: 118460

NCBI Accession: NP_478126

UniProt: Q5RKV6

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response