Tropomyosin anticorps

N° du produit ABIN2462395

Détail du produit anti-Tropomyosin anticorps

Antigène: Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

Reactivité: Humain, Rat, Souris, Poisson zèbre (Danio rerio), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Tropomyosin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TPM1.

Information d'application

Indications d'application: TPM1 antibody can be used for detection of TPM1 by ELISA at 1:312500. TPM1 antibody can be used for detection of TPM1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TPM1 antibody at -20 °C.

Détails sur Tropomyosin

Antigène: Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

Autre désignation: TPM1 (TPM1 Produits)

Synonymes: anticorps alpha-fTM, anticorps Tm7, anticorps tpm1, anticorps MGC84844, anticorps AA986836, anticorps AI854628, anticorps TM2, anticorps Tm3, anticorps Tmpa, anticorps Tpm-1, anticorps alpha-TM, anticorps Alpha-tm, anticorps Tma2, anticorps Tmsa, anticorps TPM1, anticorps fb37a09, anticorps tm, anticorps wu:fb37a09, anticorps CH1, anticorps alpha-tm, anticorps alpha-tropomyosin, anticorps C15orf13, anticorps CMD1Y, anticorps CMH3, anticorps HTM-alpha, anticorps TMSA, anticorps TPMA, anticorps Tm1, anticorps zgc:171719, anticorps zgc:55951, anticorps zgc:77009, anticorps tropomyosin 1 (alpha), anticorps tropomyosin, anticorps tropomyosin 1, anticorps tropomyosin 1, alpha, anticorps alpha-tropomyosin, anticorps tropomyosin 1 L homeolog, anticorps TPM1, anticorps tm7, anticorps Tpm1, anticorps tpma, anticorps tpm1.L, anticorps Smp_044010.2, anticorps LOC732984, anticorps tpm1

Sujet: TPM1 is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction.This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.

Poids moléculaire: 31 kDa, 33 kDa, 33 kDa, 33 kDa

ID gène: 7168

NCBI Accession: NP_000357

UniProt: P09493

Pathways: Regulation of Actin Filament Polymerization