S1PR5 anticorps

N° du produit ABIN2462616

Cet anticorps anti-S1PR5 est un anticorps Lapin Polyclonal détectant S1PR5 dans WB, ELISA et IHC. Adapté pour Humain, Souris, Rat et Chien.

Aperçu rapide pour S1PR5 anticorps (ABIN2462616)

Antigène: S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp S1PR5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-S1PR5 anticorps

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EDG8.

Information d'application

Indications d'application: EDG8 antibody can be used for detection of EDG8 by ELISA at 1:62500. EDG8 antibody can be used for detection of EDG8 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store EDG8 antibody at -20 °C.

Détails sur S1PR5

Antigène: S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))

Autre désignation: EDG8

Sujet: EDG8 is a receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. It Is coupled to both the G (i/0)alpha and G (12) subclass of heteromeric G-proteins (By similarity). It may play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.

Poids moléculaire: 44 kDa

ID gène: 53637

NCBI Accession: NP_110387

UniProt: Q9H228