S1PR5 anticorps

N° du produit ABIN2462616

Détail du produit anti-S1PR5 anticorps

Antigène: S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp S1PR5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EDG8.

Information d'application

Indications d'application: EDG8 antibody can be used for detection of EDG8 by ELISA at 1:62500. EDG8 antibody can be used for detection of EDG8 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store EDG8 antibody at -20 °C.

Détails sur S1PR5

Antigène: S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))

Autre désignation: EDG8 (S1PR5 Produits)

Synonymes: anticorps EDG8, anticorps Edg-8, anticorps S1P5, anticorps SPPR-1, anticorps SPPR-2, anticorps fd11a07, anticorps wu:fd11a07, anticorps zgc:92296, anticorps edg-8, anticorps edg8, anticorps s1p5, anticorps sppr-1, anticorps sppr-2, anticorps xts1p5, anticorps Edg8, anticorps lpB4, anticorps zgc:158362, anticorps sphingosine-1-phosphate receptor 5, anticorps sphingosine-1-phosphate receptor 5a, anticorps sphingosine-1-phosphate receptor 5b, anticorps S1PR5, anticorps s1pr5a, anticorps s1pr5, anticorps S1pr5, anticorps s1pr5b

Sujet: EDG8 is a receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. It Is coupled to both the G (i/0)alpha and G (12) subclass of heteromeric G-proteins (By similarity). It may play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.

Poids moléculaire: 44 kDa

ID gène: 53637

NCBI Accession: NP_110387

UniProt: Q9H228