UBE2D1 anticorps

N° du produit ABIN2462648

L’anticorps Lapin Polyclonal anti-UBE2D1 a été validé pour WB et ELISA. Il convient pour détecter UBE2D1 dans des échantillons de Humain, Souris, Rat et Chien.

Aperçu rapide pour UBE2D1 anticorps (ABIN2462648)

Antigène: UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2D1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-UBE2D1 anticorps

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human UBE2D1.

Information d'application

Indications d'application: UBE2D1 antibody can be used for detection of UBE2D1 by ELISA at 1:62500. UBE2D1 antibody can be used for detection of UBE2D1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store UBE2D1 antibody at -20 °C.

Détails sur UBE2D1

Antigène: UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))

Autre désignation: UBE2D1

Sujet: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D1 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.

Poids moléculaire: 16 kDa, 42 kDa

ID gène: 7321

NCBI Accession: NP_003329

UniProt: P51668

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades