IRF6 anticorps

N° du produit ABIN2462721

Détail du produit anti-IRF6 anticorps

Antigène: IRF6 (Interferon Regulatory Factor 6 (IRF6))

Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF6 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IRF6.

Information d'application

Indications d'application: IRF6 antibody can be used for detection of IRF6 by ELISA at 1:312500. IRF6 antibody can be used for detection of IRF6 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store IRF6 antibody at -20 °C.

Détails sur IRF6

Antigène: IRF6 (Interferon Regulatory Factor 6 (IRF6))

Autre désignation: IRF6 (IRF6 Produits)

Synonymes: anticorps IRF6, anticorps lps, anticorps pit, anticorps pps, anticorps vws, anticorps ofc6, anticorps xIRF-6, anticorps DKFZp469E012, anticorps LPS, anticorps OFC6, anticorps PIT, anticorps PPS, anticorps PPS1, anticorps VWS, anticorps VWS1, anticorps zgc:63500, anticorps AI876454, anticorps E230028I05Rik, anticorps mirf6, anticorps interferon regulatory factor 6, anticorps interferon regulatory factor 6 S homeolog, anticorps IRF6, anticorps irf6, anticorps irf6.S, anticorps Irf6

Sujet: IRF6 is a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in its gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.

Poids moléculaire: 65 kDa, 69 kDa

ID gène: 3664

NCBI Accession: NP_006138

UniProt: O14896