SWAP70 anticorps

N° du produit ABIN2462957

Détail du produit anti-SWAP70 anticorps

Antigène: SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SWAP70 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SWAP70.

Information d'application

Indications d'application: SWAP70 antibody can be used for detection of SWAP70 by ELISA at 1:62500. SWAP70 antibody can be used for detection of SWAP70 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SWAP70 antibody at -20 °C.

Détails sur SWAP70

Antigène: SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))

Autre désignation: SWAP70 (SWAP70 Produits)

Synonymes: anticorps SWAP-70, anticorps 70kDa, anticorps AV235546, anticorps HSPC321, anticorps swap70b, anticorps zgc:63599, anticorps switching B-cell complex subunit SWAP70, anticorps SWA-70 protein, anticorps SWAP switching B-cell complex 70, anticorps SWAP switching B-cell complex 70kDa subunit, anticorps switching B-cell complex subunit SWAP70a, anticorps SWAP70, anticorps Swap70, anticorps swap70, anticorps swap70a

Sujet: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. SWAP70 also mediates signaling of membrane ruffling. It regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.

Poids moléculaire: 69 kDa

ID gène: 23075

NCBI Accession: NP_055870

UniProt: Q9UH65

Pathways: Production of Molecular Mediator of Immune Response