LMAN1 anticorps

N° du produit ABIN2462990

L’anticorps Lapin Polyclonal anti-LMAN1 a été validé pour WB et ELISA. Il convient pour détecter LMAN1 dans des échantillons de Humain, Souris, Rat et Chien.

Aperçu rapide pour LMAN1 anticorps (ABIN2462990)

Antigène: LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LMAN1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-LMAN1 anticorps

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LMAN1.

Information d'application

Indications d'application: LMAN1 antibody can be used for detection of LMAN1 by ELISA at 1:1562500. LMAN1 antibody can be used for detection of LMAN1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store LMAN1 antibody at -20 °C.

Détails sur LMAN1

Antigène: LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))

Autre désignation: LMAN1

Sujet: LMAN1 is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in its gene are associated with a coagulation defect. Using positional cloning, its gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.

Poids moléculaire: 54 kDa

ID gène: 3998

NCBI Accession: NP_005561

UniProt: P49257