TIAL1 anticorps

N° du produit ABIN2463661

Détail du produit anti-TIAL1 anticorps

Antigène: TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))

Reactivité: Humain, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIAL1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TIAL1.

Information d'application

Indications d'application: TIAL1 antibody can be used for detection of TIAL1 by ELISA at 1:62500. TIAL1 antibody can be used for detection of TIAL1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TIAL1 antibody at -20 °C.

Détails sur TIAL1

Antigène: TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))

Autre désignation: TIAL1 (TIAL1 Produits)

Synonymes: anticorps TCBP, anticorps TIAR, anticorps 5330433G13Rik, anticorps AL033329, anticorps mTIAR, anticorps zgc:66130, anticorps tcbp, anticorps tiar, anticorps TIA1 cytotoxic granule associated RNA binding protein like 1, anticorps Tia1 cytotoxic granule-associated RNA binding protein-like 1, anticorps TIA1 cytotoxic granule-associated RNA binding protein-like 1, anticorps TIAL1, anticorps Tial1, anticorps tial1

Sujet: The protein encoded by TIAL1 is a member of a family of RNA-binding proteins and possesses nucleolytic activity against cytotoxic lymphocyte target cells. The gene product is a cytotoxic granule-associated protein and has been shown to bind specifically to poly (A) homopolymers and to fragment DNA in permeabilized target cells. It has been suggested that members of this protein family may be involved in the induction of apoptosis. One isoform contains a lysosome-targeting motif in its C-terminal auxiliary domain, however, alternative splicing results in a T-cluster DNA-binding isoform, differing at the C-terminus where a hydrophobic sequence replaces the lysosome-targeting motif.

Poids moléculaire: 42 kDa

ID gène: 7073

NCBI Accession: NP_003243

UniProt: Q01085