Caveolin 3 anticorps

N° du produit ABIN2463712

Détail du produit anti-Caveolin 3 anticorps

Antigène: Caveolin 3 (CAV3)

Reactivité: Humain, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caveolin 3 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CAV3.

Information d'application

Indications d'application: CAV3 antibody can be used for detection of CAV3 by ELISA at 1:12500. CAV3 antibody can be used for detection of CAV3 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CAV3 antibody at -20 °C.

Détails sur Caveolin 3

Antigène: Caveolin 3 (CAV3)

Autre désignation: CAV3 (CAV3 Produits)

Synonymes: anticorps LGMD1C, anticorps LQT9, anticorps VIP-21, anticorps VIP21, anticorps AI385751, anticorps Cav-3, anticorps M-cav, anticorps caveolin-3, anticorps im:6902906, anticorps zgc:109710, anticorps LOC733765, anticorps CAV3, anticorps cav3, anticorps caveolin 3, anticorps caveolin-3, anticorps CAV3, anticorps Cav3, anticorps cav3, anticorps LOC733765, anticorps cav-3

Sujet: CAV3 is a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.

Poids moléculaire: 17 kDa

ID gène: 859

NCBI Accession: NP_001225

UniProt: P56539

Pathways: Carbohydrate Homeostasis, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity