GSTP1 anticorps (truncated)

N° du produit ABIN2464062

Cet anticorps anti-GSTP1 est un anticorps Souris Monoclonal détectant GSTP1 dans WB, IHC et ELISA. Adapté pour Humain.

Aperçu rapide pour GSTP1 anticorps (truncated) (ABIN2464062)

Antigène: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GSTP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 3F2C2

Détail du produit anti-GSTP1 anticorps

Épitope: truncated

Immunogène: Ni-NTA purified truncated recombinant GSTP1 expressed in E. Coli strain BL21 (DE3).

Isotype: IgG1

Information d'application

Indications d'application: Western Blot:1:500 - 1:2,000
IHC(P):1:500 - 1:2,000
IHC(F):1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: -20 °C

Stockage commentaire: GSTP1 monoclonal antibody can be stored at -20 °C, stable for one year.

Détails sur GSTP1

Antigène: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Autre désignation: GSTP1

Sujet: GSTP1 (glutathione-S-transferase, pi 1), also called GST3/DFN7, which is located on chromosome 11q13 , is a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. GSTP1 act like a tumor suppressor gene, which when inactivated leads to tumor growth, and the -class glutathione S-transferase is commonly inactivated by somatic CpGisland hypermethylation in cancers of the prostate, liver, and breast. Methylation of regulatory sequences at the GSTP1 gene locus is found in the vast majority (>90 % ) of prostate carcinomas and is associated with transcriptional down-regulation.

ID gène: 2950

UniProt: P09211

Pathways: Cellular Response to Molecule of Bacterial Origin