Inhibin alpha anticorps (truncated)

N° du produit ABIN2464073

L’anticorps anti-Inhibin alpha Monoclonal Souris est utilisé pour la détection de Inhibin alpha dans des échantillons de Humain. Il a été validé pour WB, IHC et ELISA.

Aperçu rapide pour Inhibin alpha anticorps (truncated) (ABIN2464073)

Antigène: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Inhibin alpha est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 4A2A9-4A2F7-4A2F2

Détail du produit anti-Inhibin alpha anticorps

Épitope: truncated

Purification: Antibody is purified by protein A affinity chromatography.

Immunogène: Ni-NTA purified truncated recombinant INHA expressed in E. Coli strain BL21 (DE3).

Isotype: IgG1

Information d'application

Indications d'application: Western Blot:1:500 - 1:1,000
IHC(P):1:1,000 - 1:2,000
ELISA:Propose dilution 1:10,000
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Buffer: Purified antibody in PBS containing 0.03 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: -20 °C

Stockage commentaire: INHA(Inhibin alpha) monoclonal antibody can be stored at -20 °C, stable for one year.

Détails sur Inhibin alpha

Antigène: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Autre désignation: INHA

Sujet: INHA(A-inhibin subunit precursor, inhibin alpha subunit ),also called inhibin(alpha) ,which is located on chromosome 2q33-q36. Inhibin is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises of two subunits,Inhibin A and B. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa cell tumors and can therefore be used as a marker for primary as well as recurrent disease. In addition to their role in endocrine feedback in the reproductive sytem, inhibins subserve local regulatory roles in numerous extragonadal tissues, including brain, adrenal,bone marrow, placenta, and most notably anterior pituitary. Inhibin alpha subunit gene expression is down regulated in human prostate cancer, suggesting a tumor suppressive role.

ID gène: 3623

UniProt: P05111

Pathways: Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion