Lipase A anticorps (truncated)

N° du produit ABIN2464075

Détail du produit anti-Lipase A anticorps

Antigène: Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))

Épitope: truncated

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Lipase A est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A affinity chromatography.

Immunogène: Ni-NTA purified truncated recombinant LAL expressed in E. Coli strain BL21 (DE3).

Clone: 9G7F12

Isotype: IgG2a

Information d'application

Indications d'application: Western Blot:Dilution 1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Buffer: Purified antibody in PBS containing 0.03 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: -20 °C

Stockage commentaire: LAL monoclonal antibody can be stored at -20 °C, stable for one year.

Détails sur Lipase A

Antigène: Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))

Autre désignation: LAL (LIPA Produits)

Synonymes: anticorps cesd, anticorps lal, anticorps LIPA, anticorps CESD, anticorps LAL, anticorps Chole, anticorps Chole2, anticorps Lip1, anticorps AA960673, anticorps Lal, anticorps Lip-1, anticorps lipase A, lysosomal acid type, anticorps lipase A, lysosomal acid, cholesterol esterase, anticorps lipase A, lysosomal acid, cholesterol esterase L homeolog, anticorps lysosomal acid lipase A, anticorps LIPA, anticorps lipa, anticorps lipa.L, anticorps Lipa

Sujet: Lysosomal acid lipase (LAL), with 378-amino acid protein( 43-54 kDa), functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides which are taken up by receptor-mediated endocytosis. An inherited deficiency or low activity of human lysosomal acid lipase results in the intralysosomal storage of the respective lipid substrates. So it is also responsible for the rare conditions of Wolman disease and cholesteryl ester storage disease (CESD). As the enzyme is synthesized by all nucleated cells, lipid-laden cells are found in all organs, particularly in liver, spleen, the adrenal and the hemopoietic system, and in the intestine as well as in the lymph nodes, lungs, testes, and ovaries.

ID gène: 3988

UniProt: P38571