ASPSCR1
Reactivité: Humain
WB
Hôte: Lapin
Monoclonal
unconjugated
Indications d'application
Western Blot:1:500 - 1:2,000 ELISA:Propose dilution 1:10,000. Determining optimal working dilutions by titration test.
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified antibody in PBS containing 0.03 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Stock
-20 °C
Stockage commentaire
Mouse TUG monoclonal antibody can be stored at -20 °C, stable for one year.
Antigène
ASPSCR1
(Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))
Autre désignation
TUG
Sujet
The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.