MYST1 anticorps (truncated)

N° du produit ABIN2464086

Cet anticorps anti-MYST1 Monoclonal Souris (Clone 8C4C4) (ABIN2464086) détecte spécifiquement MYST1 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour MYST1 anticorps (truncated) (ABIN2464086)

Antigène: MYST1 (KAT8) (K(lysine) Acetyltransferase 8 (KAT8))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MYST1 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 8C4C4

Détail du produit anti-MYST1 anticorps

Épitope: truncated

Immunogène: Ni-NTA purified truncated recombinant MYST1-trx expressed in E. Coli strain BL21 (DE3).

Isotype: IgG2b

Information d'application

Indications d'application: Western Blot:1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: -20 °C

Stockage commentaire: MYST1 monoclonal antibody can be stored at -20 °C, stable for one year.

Détails sur MYST1

Antigène: MYST1 (KAT8) (K(lysine) Acetyltransferase 8 (KAT8))

Autre désignation: MYST1

Sujet: MYST1 (MYST histone acetyltransferase 1,MOF) belongs to the MYST family of histone acetyltransferases, which are employed in the cell to bring about transcriptional regulation. The MYST family includes MYST1, is named for the founding members MOZ, yeast YBF2 and SAS2, and TIP60. All members of this family contain a MYST region of about 240 amino acids with a canonical acetyl-CoA-binding site and a C2HC-type zinc finger motif. Most MYST proteins also have a chromodomain involved in protein- protein interactions and targeting transcriptional regulators to chromatin. Although MOF is expressed in both males and females, it associates with the X chromosome only in males. MOF contains a zinc-finger domain that is used to contact the globular part of the nucleosome and histone H4. The carboxy terminal domain of human MOF also has histone acetyltransferase activity directed against histones H3 and H2A, a characteristic shared with other MYST family histone.

ID gène: 84148

UniProt: Q9H7Z6