Bloom Syndrome (pSer527) anticorps

N° du produit ABIN2464127

L’anticorps Lapin Polyclonal anti- a été validé pour IHC, ELISA et WB. Il convient pour détecter dans des échantillons de Humain, Souris, Non-Human Primate et Rat.

Aperçu rapide pour Bloom Syndrome (pSer527) anticorps (ABIN2464127)

Antigène: Bloom Syndrome

Reactivité: Humain, Souris, Non-Human Primate, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Immunohistochemistry (IHC), ELISA, Western Blotting (WB)

Détail du produit

Épitope: pSer527

Purification: Affinity Purified

Immunogène: A synthetic peptide surrounding amino acid S527

Isotype: IgG

Information d'application

Indications d'application: ELISA, Western (immuno) blotting, Immunostaining (in testing)

Restrictions: For Research Use only

Stockage

Détail du antigène

Antigène: Bloom Syndrome

Sujet: The Bloom syndrome gene product is a member of the RecQ helicase protein family. The protein contains 1417 amino acids, including one ATP binding site, one DEAH box, and two putative nuclear localization signals, as well as phosphorylation sites. BLS protein is known to associate and be phosphorylated by the ATR (ataxia telangiectasia, rad3+) protein, in response to genetic stress. The Bloom's syndrome gene product is thought to play a role in the etiology of two major human health problems, each of which is a very common complication of Bloom's syndrome, namely cancer and diabetes.

ID gène: 641

UniProt: P54132