Huntingtin anticorps (N-Term)
Aperçu rapide pour Huntingtin anticorps (N-Term) (ABIN2464133)
Antigène
Voir toutes Huntingtin (HTT) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Purification
- Affinity Purified
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Immunogène
- A synthetic peptide corresponding to the N-terminus.
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Isotype
- IgG
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Indications d'application
- ELISA, Western (immuno) blotting, Immunostaining (in testing)
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Restrictions
- For Research Use only
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- Huntingtin (HTT)
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Autre désignation
- Huntington Protein
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Sujet
- Huntington's disease (HD) is an autosomal dominant neurological disorder caused by a polyglutamine (polyQ) repeat expansion in the huntingtin (Htt) protein. The disease is characterized by neurodegeneration and formation of neuronal intracellular inclusions primarily in the striatum and cortex, leading to personality changes, motor impairment, and dementia. The Huntington s disease protein is ~350 kDa in size and is localized in the brain.
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ID gène
- 3064
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UniProt
- P42858
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Pathways
- Signalisation PI3K-Akt, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport
Antigène
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