TK1 anticorps

N° du produit ABIN2466869

L’anticorps Souris Monoclonal anti-TK1 a été validé pour WB et ELISA. Il convient pour détecter TK1 dans des échantillons de Humain.

Aperçu rapide pour TK1 anticorps (ABIN2466869)

Antigène: TK1 (Thymidine Kinase 1, Soluble (TK1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TK1 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 3B3-E11

Détail du produit anti-TK1 anticorps

Purification: Protein G-purified

Immunogène: 5 -His-tagged recombinant human thymidine kinase.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C

Stockage commentaire: Thymidine Kinase monoclonal antibody can be stored at 4 °C, stable for one year.

Détails sur TK1

Antigène: TK1 (Thymidine Kinase 1, Soluble (TK1))

Autre désignation: Thymidine Kinase

Sujet: Thymidine kinase (TK) belongs to a group of enzymes such as dihydrofolate reductase, thymidylate synthase, and DNA polymerase that are involved in DNA synthesis and precursor production. High levels of these enzymes are present in proliferating cells, and low levels are found in resting cells, due to multiple regulatory mechanisms that ensure exclusive expression of these enzymes in replicating cells. TK is responsible for catalyzing the phosphorylation of thymidine, which functions as a part of the pyrimidine salvage pathway involved in DNA synthesis. The activities of enzymes such as TK are essential for the activation of several chemotherapeutically important nucleoside analogues that are administered as prodrugs.

ID gène: 3978

UniProt: P18858