PPFIA1
Reactivité: Humain, Souris
WB, IP
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
PTPRF interacting protein alpha 1 isoform b variant antibody can be used for the detection of PTPRF interacting protein alpha 1 isoform b variant by Western Blot.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate-Buffered Saline. No preservatives added.
Agent conservateur
Without preservative
Conseil sur la manipulation
As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Stock
4 °C/-20 °C
Stockage commentaire
PPFIA1 antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.
Antigène
PPFIA1
(Protein Tyrosine Phosphatase F Interacting Protein 1 (PPFIA1))
anticorps LIP.1, anticorps LIP1, anticorps LIPRIN, anticorps C030014K08Rik, anticorps C87158, anticorps PTPRF interacting protein alpha 1, anticorps protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1, anticorps PPFIA1, anticorps Ppfia1
Sujet
The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described.