SH3GL1
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
RB37000
unconjugated
Indications d'application
SH3-containing Grb-2-like 1 protein antibody can be used for the detection of SH3-containing Grb-2-like 1 protein by Western Blot.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate-Buffered Saline. No preservatives added.
Agent conservateur
Without preservative
Conseil sur la manipulation
As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Stock
4 °C/-20 °C
Stockage commentaire
SH3GL1 antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.
Antigène
SH3GL1
(SH3-Domain GRB2-Like 1 (SH3GL1))
Autre désignation
SH3GL1
Sujet
SH3GL1 may play a regulatory role in synaptic vesicle recycling. It interacts with SYNJ1 and DNM1 through its SH3 domain with the proline-rich region of mixed lineage Leukemia (MLL) in either the fusion or the normal MLL protein. This protein is located in cytoplasmic, and peripheral membrane protein associated with internal membranes. Concentrated in presynaptic nerve terminals in neurons (By similarity). It s expressed ubiquitously. Higher expression in pancreas, placenta, prostate, testis and uterus. In some cases of acute leukemia, a translocation results in the formation of a MLL-EEN fusion gene.