PDE8B anticorps (Internal Region)

N° du produit ABIN2469456

Cet anticorps anti-PDE8B Polyclonal Lapin (ABIN2469456) détecte spécifiquement PDE8B dans IHC. L’anticorps est réactif avec des échantillons de Humain, Singe, Gibbon et Gorilla.

Aperçu rapide pour PDE8B anticorps (Internal Region) (ABIN2469456)

Antigène: PDE8B (phosphodiesterase 8B (PDE8B))

Reactivité: Humain, Singe, Gibbon, Gorilla

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE8B est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-PDE8B anticorps

Épitope: Internal Region

Specificité: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Immunoaffinity Chromatography

Immunogène: PDE8B antibody was raised against a peptide located near the internal domain of PDE8B (Human).

Information d'application

Indications d'application: PDE8B antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies avoid freeze/thaw cycles.

Stock: 4 °C/-80 °C

Stockage commentaire: PDE8B antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Détails sur PDE8B

Antigène: PDE8B (phosphodiesterase 8B (PDE8B))

Autre désignation: PDE8B

Sujet: Phosphodiesterase 8B, is a high affinity, cAMP-specific phosphodiesterase. Enhanced PDE8B activity has been associated with the phenotypic expression of Gsalpha mutations in human pituitary tumors. PDE8B is absent in normal pituitary but present in GH-secreting adenomas. PDE8B activity is inhibited by dipyridamole, but it is insensitive to rolipram, zaprinast, or IBMX.

ID gène: 8622

UniProt: O95263

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process