SGK3 anticorps (C-Term)

N° du produit ABIN2469462

Cet anticorps anti-SGK3 Polyclonal Lapin (ABIN2469462) détecte spécifiquement SGK3 dans IHC et ELISA. L’anticorps est réactif avec des échantillons de Humain, Lapin, Singe, Gibbon, Gorilla et Orang-Utan.

Aperçu rapide pour SGK3 anticorps (C-Term) (ABIN2469462)

Antigène: SGK3 (serum/glucocorticoid Regulated Kinase Family, Member 3 (SGK3))

Reactivité: Humain, Lapin, Singe, Gibbon, Gorilla, Orang-Utan

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SGK3 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-SGK3 anticorps

Épitope: C-Term

Specificité: BLAST analysis of the peptide immunogen showed no homology with other human proteins, except SGK1 (59 % ).

Purification: Immunoaffinity Chromatography

Immunogène: SGK3 antibody was raised against a peptide located in the C-Terminal domain of SGK3 (Human).

Information d'application

Indications d'application: SGK3 antibody can be used in immunohistochemistry starting at 14 - 28 μg/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies avoid freeze/thaw cycles.

Stock: 4 °C/-80 °C

Stockage commentaire: SGK3 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Détails sur SGK3

Antigène: SGK3 (serum/glucocorticoid Regulated Kinase Family, Member 3 (SGK3))

Autre désignation: SGK3

Sujet: SGKL/SGK3, also known as CISK for cytokine-independent survival kinase, is a SGK type protein kinase. The protein contains a lipid-binding phox homology (PX) domain, which is required for targeting SGKL/SGK3 protein to the endosomal compartment. SGKL/SGK3 functions downstream of the phosphoinositide 3-kinase (PI3K) cascade and has been implicated in cell survival. The protein has been shown to be phosphorylated and activated by 3-phosphoinositide-dependent protein kinase 1 (PDK1), and to a lesser extent insulin-like growth factor-1, in vitro. Activated SGKL/SGK3 has been shown to phosphorylate glycogen synthase kinase 3 beta (GSK-3beta) in vitro.

ID gène: 23678

UniProt: Q96BR1