HAVCR1 anticorps (AA 200-300)

N° du produit ABIN2470107

Cet anticorps anti-HAVCR1 est un anticorps Lapin Polyclonal détectant HAVCR1 dans WB et IHC. Adapté pour Humain et Souris.

Aperçu rapide pour HAVCR1 anticorps (AA 200-300) (ABIN2470107)

Antigène: HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HAVCR1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-HAVCR1 anticorps

Épitope: AA 200-300

Purification: Protein G Column

Immunogène: HAVCR1 antibody was raised against amino acids 200 - 300 of HAVCR1 (Human).

Isotype: IgG

Information d'application

Indications d'application: HAVCR1 antibody can be used in immunohistochemistry starting at 5 μg/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, 0.05 % BSA, 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store HAVCR1 antibody at 4 °C for short term applications. For long term storage, aliquot and -20 °C.

Détails sur HAVCR1

Antigène: HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

Autre désignation: HAVCR1

Classe de substances: Virus

Sujet: HAVCR1, a 359 A.A Class 1 integral membrane glycoprotein, is used by Hepatitis A virus to infect humans. It consists of a conserved N-terminal Cys-rich region, IgV (Immunoglobulin Variable region like) domain and a TSP-rich mucin domain in the extracellular region followed by a highly conserved tyrosine kinase phosphorylation motif in the cytoplasmic region. HAVCR1 is expressed on terminally differentiated CD4+ Th2 cells and regulates cytokine production. It plays an important role in the regulation of immune responses in the development of asthma and allergic responses. Its expression is critically upregulated in dedifferentiated kidney cells, thus indicating a possible role in regeneration of proximal tubule epithelium in Kidneys. HAVCR1 has shown to be upregulated in renal carcinomas, suggesting its role in tumor progression and metastasis.

ID gène: 26762

UniProt: Q96D42