SIRT7 anticorps (AA 35-51)

N° du produit ABIN2470139

L’anticorps Lapin Polyclonal anti-SIRT7 a été validé pour WB et IHC. Il convient pour détecter SIRT7 dans des échantillons de Humain.

Aperçu rapide pour SIRT7 anticorps (AA 35-51) (ABIN2470139)

Antigène: SIRT7 (Sirtuin 7 (SIRT7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIRT7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-SIRT7 anticorps

Épitope: AA 35-51

Purification: Protein G Column

Immunogène: SIRT7 antibody was raised against amino acids 35 - 51 of SIRT7 (Human).

Isotype: IgG

Information d'application

Indications d'application: SIRT7 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 2.5 μg/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, 0.2 % gelatin, 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies avoid freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Product should be stored long term (months) at -20 °C and short term (weeks) at 4 °C.

Détails sur SIRT7

Antigène: SIRT7 (Sirtuin 7 (SIRT7))

Autre désignation: SIRT7

Sujet: SIRT7 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine groups of acetylated histones.

ID gène: 51547

UniProt: Q9NRC8