MYL9 anticorps (C-Term)
Aperçu rapide pour MYL9 anticorps (C-Term) (ABIN2470242)
Antigène
Voir toutes MYL9 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Purification
- Immunoaffinity Chromatography
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Immunogène
- MYL9 antibody was raised against amino acids 12-27 from the C-Terminus of human myosin light chain protein.
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Indications d'application
- MYL9 antibody can be used in immunohistochemistry starting at 2.5 - 5 μg/mL, and flow cytometry.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- As with all antibodies avoid freeze/thaw cycles.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store MYL9 antibody at 4 °C or -20 °C.
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- MYL9 (Myosin Regulatory Light Polypeptide 9 (MYL9))
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Autre désignation
- MYL9
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Sujet
- Myosin is the major component of thick muscle filaments, and is a long asymmetric molecule containing a globular head and a long tail. The molecule consists of two heavy chains each ~200,000 daltons, and four light chains each ~16,000 - 21,000 daltons. Activation of smooth and cardiac muscle primarily involves pathways that increase calcium and myosin phosphorylation resulting in contraction. Myosin light chain phosphatase acts to regulate muscle contraction by dephosphorylating activated myosin light chain. The selected peptide sequence used to generate the polyclonal antibody is located near the amino terminal end of the polypeptide corresponding to the smooth/non-muscle form of myosin regulatory light chain found in cardiac myocytes in addition to smooth and non-muscle cells. This sequence differs from that of the sarcomeric/ cardiac form of myosin regulatory light chain that has a different sequence around the phosphorylation site. Human, mouse and rat have almost identical sequences.
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ID gène
- 10398
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UniProt
- P24844
Antigène
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