PSMA anticorps (C-Term)

N° du produit ABIN2470727

L’anticorps Lapin Polyclonal anti-PSMA a été validé pour IHC. Il convient pour détecter PSMA dans des échantillons de Humain.

Aperçu rapide pour PSMA anticorps (C-Term) (ABIN2470727)

Antigène: PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMA est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-PSMA anticorps

Épitope: C-Term

Purification: Immunoaffinity Chromatography

Immunogène: FOLH1 antibody was raised against amino acids from the C-Terminus of FOLH1 (Human).

Information d'application

Indications d'application: FOLH1 antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 10 μg/mL, and immunoprecipitation

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM PBS, pH 7.4, BSA, sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies avoid freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store FOLH1 antibody at 4 °C or -20 °C.

Détails sur PSMA

Antigène: PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))

Autre désignation: FOLH1

Sujet: PMSA (FOLH1) is a type II transmembrane glycoprotein belonging to the M28 peptidase family. Three functionally distinct proteins are encoded, including poly-gamma-glutamate carboxypeptidase in the intestine, N-acetylated alpha-linked acidic dipeptidase 1 in the brain, and prostate- specific membrane antigen in the prostate. A mutation in the intestinal form may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. The form expressed in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. The prostate form is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region.

ID gène: 2346

UniProt: Q04609