Cholera Toxin beta anticorps

N° du produit ABIN2472974

Détail du produit anti-Cholera Toxin beta anticorps

Antigène: Cholera Toxin beta

Reactivité: Vibrio cholerae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cholera Toxin beta est non-conjugé

Application: ELISA, Immunodiffusion (ID)

Fonction: Rabbit anti cholera toxin beta antibody recognizes the beta subunit of cholera toxin.

Attributs du produit: Purified Ig

Purification: Purified

Immunogène: Purified choleragenoid

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 4.0 mg/mL

Buffer: Phosphate buffered saline, 0.1% Sodium Azide (NaN3)

Conseil sur la manipulation: This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended.

Date de péremption: 18 months

Références pour anticorps anti-Cholera Toxin beta (ABIN2472974)

Thangawng, Kim, Golden, Anderson, Robertson, Low, Ligler: "A hard microflow cytometer using groove-generated sheath flow for multiplexed bead and cell assays." dans: Analytical and bioanalytical chemistry, Vol. 398, Issue 5, pp. 1871-81, (2010) (PubMed).

Détails sur Cholera Toxin beta

Antigène: Cholera Toxin beta

Abstract: Cholera Toxin beta Produits

Sujet: The beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin alpha subunit into cells. The holotoxin consists of a pentameric ring of beta subunits whose central pore is occupied by the alpha subunit. The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The alpha subunit (and cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.

UniProt: P01556