Transferrin anticorps (N-Term)

N° du produit ABIN2476916

L’anticorps Souris Monoclonal anti-Transferrin a été validé pour WB, ELISA, IF et Func. Il convient pour détecter Transferrin dans des échantillons de Humain, Rat, Porc et Lapin.

Aperçu rapide pour Transferrin anticorps (N-Term) (ABIN2476916)

Antigène: Transferrin (TF)

Reactivité: Humain, Rat, Porc, Lapin

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Transferrin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Functional Studies (Func)

Clone: HTF-14

Détail du produit anti-Transferrin anticorps

Épitope: N-Term

Specificité: Anti transferrin clone HTF-14 is specific for the N-terminal domain of human transferrin and has been shown to block binding of transferrin to the transferrin receptor (CD71). Clone HTF-14 is not able to recognise receptor bound transferrin. Clone HTF-14 recognises a conformational epitope in a loop of the N lobe of transferrin involving the critical Lys-144 residue, also essential for binding of the N lobe to the transferrin receptor (Mason et al.2009)Transferrin is a 77 kDa plasma protein synthesized by the liver involved with the transport of iron. Each transferrin molecule has two domains, both with facility to carry 2 ferric ions. The iron/transferrin complex is essential for haemoglobin synthesis and certain types of cell division.

Réactivité croisée: Porc, Lapin, Rat (Rattus)

Attributs du produit: Purified IgG

Purification: Purified

Immunogène: Purified porcine transferrin

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Détails sur Transferrin

Antigène: Transferrin (TF)

Autre désignation: TRANSFERRIN

ID gène: 7018

UniProt: P02787

Pathways: Transition Metal Ion Homeostasis