GRIN2B anticorps (AA 20-271) (PE)
Aperçu rapide pour GRIN2B anticorps (AA 20-271) (PE) (ABIN2483221)
Antigène
Voir toutes GRIN2B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 20-271
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Specificité
- Detects ~166 kDa. No cross-reactivity against NR2A.
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Réactivité croisée
- Humain, Souris, Rat
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Purification
- Protein G Purified
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Immunogène
- Fusion protein amino acids 20-271 (extracellular N-terminus) of rat NR2B
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Isotype
- IgG2b
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Indications d'application
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- WB (1:1000)
- IHC (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
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Commentaires
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1 μg/ml of ABIN2483221 was sufficient for detection of NR2B in 10 μg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Conjugated antibodies should be stored at 4°C
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- GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))
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Autre désignation
- NR2B
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Sujet
- NR2B containing receptors have been implicated in synaptic plasticity, memory formation and pain modulation (1). Studies suggest that the NR2B subunit of glutamate receptors may be potential targets for relieving pain, NR2B may be a probable target for anti-nociceptive drugs, and may also be useful as analgesics (2).
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ID gène
- 24410
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NCBI Accession
- NP_036706
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UniProt
- Q00960
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Pathways
- Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity
Antigène
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