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BCAN anticorps (AA 219-655) (Atto 488)

BCAN Reactivité: Rat WB, ICC, IF Hôte: Souris Monoclonal S294A-6 Atto 488
N° du produit ABIN2483309
  • Antigène Voir toutes BCAN Anticorps
    BCAN (Brevican (BCAN))
    Épitope
    • 13
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 219-655
    Reactivité
    • 32
    • 20
    • 8
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Rat
    Hôte
    • 26
    • 22
    • 2
    Souris
    Clonalité
    • 30
    • 20
    Monoclonal
    Conjugué
    • 22
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BCAN est conjugé à/à la Atto 488
    Application
    • 40
    • 20
    • 17
    • 16
    • 15
    • 13
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificité
    Detects ~140 kDa (and smaller due to proteolytic cleavage).
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Protein G Purified
    Immunogène
    Fusion protein amino acids 219-655 of rat Brevican
    Clone
    S294A-6
    Isotype
    IgG2b
    Top Product
    Discover our top product BCAN Anticorps primaire
  • Indications d'application
    • WB (1:1000)
    • optimal dilutions for assays should be determined by the user.
    Commentaires

    1 μg/ml of ABIN2483309 was sufficient for detection of Brevican in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Conjugated antibodies should be stored at 4°C
  • Antigène
    BCAN (Brevican (BCAN))
    Autre désignation
    Brevican (BCAN Produits)
    Synonymes
    anticorps fi32a12, anticorps wu:fi32a12, anticorps BCAN, anticorps Xbcan, anticorps Cspg7, anticorps ALPBRE, anticorps BEHAB, anticorps CSPG7, anticorps brevican, anticorps brevican L homeolog, anticorps bcan, anticorps BCAN, anticorps bcan.L, anticorps Bcan
    Sujet
    Brevican is the most abundant chondroitin sulfate proteoglycan in the extracellular matrix of the adult brain. It is a member of the lectican family of aggregating extracellular matrix proteoglycans that bear chondroitin sulfate (CS) chains. It is highly expressed in the central nervous system and is thought to stabilize synapses and inhibit neural plasticity. Brevican is secreted from astrocytes and neurons as a 145 kD core protein that bears up to three, covalently-linked, CS chains. It is also is secreted as a 145 kD core protein without CS chains. When cleaved by extracellular glutamyl endopeptidases, the ADAMTSs, a 55 kD N-terminal fragment is formed that contains the unique C terminal epitope EAMESE.
    ID gène
    25393
    NCBI Accession
    NP_001028837
    UniProt
    P55068
    Pathways
    Glycosaminoglycan Metabolic Process
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