LRP4 anticorps (AA 26-350) (PE)
Aperçu rapide pour LRP4 anticorps (AA 26-350) (PE) (ABIN2483391)
Antigène
Voir toutes LRP4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 26-350
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Specificité
- Detects the extracellular domain of LRP4 ~215 kDa. Degradation product can be seen at ~150 kDa.
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Réactivité croisée
- Humain, Souris, Rat
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Purification
- Protein G Purified
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Immunogène
- Fusion protein amino acids 26- 350 (extracellular N-terminus) of mouse LTP4
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Isotype
- IgG2a
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Indications d'application
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
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Commentaires
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1 μg/ml of ABIN2483391 was sufficient for detection of LRP4 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Conjugated antibodies should be stored at 4°C
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- LRP4 (Low Density Lipoprotein Receptor-Related Protein 4 (LRP4))
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Autre désignation
- LRP4
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Sujet
- Potential cell surface endocytic receptor, which binds and internalizes extracellular ligands for degradation by lysosomes. It is involved in the negative regulation of the canonical Wnt signaling pathway, being able to antagonize the LRP6-mediated activation of this pathway.
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ID gène
- 83469
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NCBI Accession
- NP_766256
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UniProt
- Q8VI56
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Pathways
- Skeletal Muscle Fiber Development
Antigène
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