ASIC1 anticorps (AA 460-526) (HRP)
Aperçu rapide pour ASIC1 anticorps (AA 460-526) (HRP) (ABIN2483694)
Antigène
Voir toutes ASIC1 (ACCN2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 460-526
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Specificité
- Detects ~60 kDa.
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Réactivité croisée
- Humain, Souris, Rat
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Purification
- Protein G Purified
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Immunogène
- Fusion protein amino acids 460-526 (Cytoplasmic C-terminus) of mouse ASIC1
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Isotype
- IgG1
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Indications d'application
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- WB (1:1000)
- optimal dilutions for assays should be determined by the user.
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Commentaires
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1 μg/ml of ABIN2483694 was sufficient for detection of ASIC1 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Conjugated antibodies should be stored at 4°C
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- ASIC1 (ACCN2) (Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2))
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Autre désignation
- ASIC1
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Sujet
- Acid sensing ion channel ASIC1, also designated ACCN2, BNAC2 and ASIC1a, is present in brain as a 4.3-kb transcript with localization to rat dorsal root ganglia. Insitu hybridization of rat brain suggests that ASIC1 is most abundant in the main olfactory bulb, cerebral cortex, hippocampal formation, habenula, basolateral amygdaloid nuclei and cerebellum. ASIC1 and H+-gated currents may contribute to the development of fear and anxiety.
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ID gène
- 11419
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NCBI Accession
- NP_033727
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UniProt
- Q6NXK8
Antigène
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