ADRA2C anticorps (AA 442-462) (APC)
Aperçu rapide pour ADRA2C anticorps (AA 442-462) (APC) (ABIN2485207)
Antigène
Voir toutes ADRA2C AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 442-462
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Specificité
- Detects 50 kDa or larger (possibly due to dimerization). Does not cross-react with other adrenergic receptors.
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Réactivité croisée
- Humain, Souris
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Purification
- Protein G Purified
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Immunogène
- Synthetic peptide amino acids 442- 462 (QDFRRSFKHILFRRRRRGFRQ, cytoplasmic C-terminus) of human Alpha-2C adrenergic receptor
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Isotype
- IgG1
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Indications d'application
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- WB (1:1000)
- optimal dilutions for assays should be determined by the user.
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Commentaires
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1 μg/ml of ABIN2485207 was sufficient for detection of Alpha2C Adrenergic Receptor in 20 μg of COS cells transiently transfected with HA-tagged Alpha- lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Conjugated antibodies should be stored at 4°C
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- ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))
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Autre désignation
- Alpha2C Adrenergic
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Sujet
- The alpha 2C Adrenergic Receptor controls the release of neurotransmitter from central adrenergic neurons and from sympathetic nerves in the heart. This receptor also plays a role in cognitive and behavioral function. Two variants are produced by alternative splicing. Alpha 2C Adrenergic Receptor has been reported extensively in the brain. Blood, corpus cavermosum, kidney, and heart tissues have also been reported to express the protein.
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ID gène
- 152
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NCBI Accession
- NP_000674
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UniProt
- P18825
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Pathways
- EGFR Signaling Pathway, cAMP Metabolic Process
Antigène
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