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Aquaporin 4 anticorps (C-Term) (PE)

AQP4 Reactivité: Rat WB, IHC, IF, ICC Hôte: Lapin Polyclonal PE
N° du produit ABIN2486399
  • Antigène Voir toutes Aquaporin 4 (AQP4) Anticorps
    Aquaporin 4 (AQP4)
    Épitope
    • 20
    • 16
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 65
    • 58
    • 58
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    Rat
    Hôte
    • 73
    • 18
    • 1
    Lapin
    Clonalité
    • 72
    • 20
    Polyclonal
    Conjugué
    • 49
    • 11
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Aquaporin 4 est conjugé à/à la PE
    Application
    • 74
    • 46
    • 25
    • 25
    • 21
    • 15
    • 14
    • 14
    • 13
    • 13
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    Detects ~35 kDa. May detect larger glycosylated bands ~50 kDa.
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Protein A Purified
    Immunogène
    Produced against the C-terminal peptide (Sequence N-CTKGSYMEVEDNRSQVETED) of rat aquaporin 4
    Top Product
    Discover our top product AQP4 Anticorps primaire
  • Indications d'application
    • WB (1:2000)
    • IHC (1:200)
    • ICC/IF (1:400)
    • optimal dilutions for assays should be determined by the user.
    Commentaires

    0.5 μg/ml of ABIN2486399 was sufficient for detection of aquaporin 4 in 10 μg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Conjugated antibodies should be stored at 4°C
  • Antigène
    Aquaporin 4 (AQP4)
    Autre désignation
    Aquaporin 4 (AQP4 Produits)
    Synonymes
    anticorps zgc:100922, anticorps si:ch211-192k9.1, anticorps AQP4, anticorps LOC100232616, anticorps HMIWC2, anticorps MIWC, anticorps WCH4, anticorps AQP-4, anticorps AQP4.M23, anticorps MIWC2, anticorps Miwc, anticorps aquaporin-4, anticorps aquaporin 4, anticorps aquaporin 4 L homeolog, anticorps aqp4, anticorps AQP4, anticorps aqp4.L, anticorps Aqp4
    Sujet
    Aquaporins selectively conduct water molecules in and out of the cell, while preventing the passage of ions and other solutes. Known as water channels, they are integral membrane pore proteins (1, 2). Aquaporin 4 is constitutively expressed in the basolateral cell membrane of principal collecting duct cells in the kidney and provide a pathway for water to exit these cells (3). It is also expressed in astrocytes and is up regulated by direct insult to the CNS (4). Aquaporin 4 has been proposed as the primary autoimmune target in neuromyelitis optica ( 5, 6).
    ID gène
    25293
    NCBI Accession
    NP_036957
    UniProt
    P47863
    Pathways
    Sensory Perception of Sound
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