Abeta 1-42 anticorps

N° du produit ABIN249343

Détail du produit anti-Abeta 1-42 anticorps

Antigène: Abeta 1-42 (Amyloid beta 1-42 (Abeta 1-42))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Abeta 1-42 est non-conjugé

Application: Western Blotting (WB), ELISA, Dot Blot (DB), Immunolocalization (IL)

Réactivité croisée (Details): Not reactive in: no confirmed exceptions from predicted reactivity known in the moment

Homologie: bovine, chicken, dog, porcine, rabbit

Attributs du produit: Expected / apparent Molecular Weight of the Antigene: 4.5 kDa

Purification: serum

Immunogène: synthetic peptide chosen from human Abeta (1-42) protein. Amino acid sequence: D-A-E-F-R-H-D-S-G-Y-E-V-H-H-Q-K-L-V-F-F-A-E-D-V-G-S-N-K-G-A-I-I-G-L-M-V-G-G-V-V-I-A

Information d'application

Indications d'application: 1:1000 (DB), 1:3000 (ELISA), 1-2 μg/mL (IL)

Commentaires:

the antibody can detect Abeta (1-42), Abeta (1-28) Abeta (1-20) and Abeta (1-17). This product exhibits a low reactivity to monomeric Abeta (1-42) as determined by SDS-PAGE and Western blotting.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: For reconstitution add 100 μL of sterile water.

Conseil sur la manipulation: Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
Once reconstituted make aliquots to avoid repreated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.

Références pour anticorps anti-Abeta 1-42 (ABIN249343)

Lindhagen-Persson, Brännström, Vestling, Steinitz, Olofsson: "Amyloid-? oligomer specificity mediated by the IgM isotype--implications for a specific protective mechanism exerted by endogenous auto-antibodies." dans: PLoS ONE, Vol. 5, Issue 11, pp. e13928, (2010) (PubMed).

Détails sur Abeta 1-42

Antigène: Abeta 1-42 (Amyloid beta 1-42 (Abeta 1-42))

Autre désignation: Amyloid-beta 42 protein (Abeta (1-42)) (Abeta 1-42 Produits)

Synonymes: anticorps amyloid beta precursor protein, anticorps App, anticorps APP

Sujet: Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the growing population of elderly people. A hallmark of AD is the accumulation of plaques in the brain of AD patients. The plaques predominantly consist of aggregates of amyloid-beta (Abeta), a peptide of 39-42 amino acids generated in vivo by specific, proteolytic cleavage of the amyloid precursor protein P05067

Poids moléculaire: 4.5 kDa