DHRS2 anticorps (AA 61-160) (HRP)

N° du produit ABIN2559684

L’anticorps anti-DHRS2 Polyclonal Lapin est utilisé pour la détection de DHRS2 dans des échantillons de Humain. Il a été validé pour WB, IHC (p) et IHC (fro).

Aperçu rapide pour DHRS2 anticorps (AA 61-160) (HRP) (ABIN2559684)

Antigène: DHRS2 (Dehydrogenase/reductase (SDR Family) Member 2 (DHRS2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DHRS2 est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-DHRS2 anticorps (HRP)

Épitope: AA 61-160

Fonction: DHRS2 Polyclonal Antibody, HRP Conjugated

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DHRS2

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur DHRS2

Antigène: DHRS2 (Dehydrogenase/reductase (SDR Family) Member 2 (DHRS2))

Autre désignation: DHRS2

Sujet:

Synonyms: HEP27, SDR25C1, Dehydrogenase/reductase SDR family member 2, mitochondrial, Dicarbonyl reductase HEP27, Protein D, DHRS2

Background: Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21.

ID gène: 10202

UniProt: Q13268

Pathways: C21-Steroid Hormone Metabolic Process