CRBN anticorps (PE)
Aperçu rapide pour CRBN anticorps (PE) (ABIN2559686)
Antigène
Voir toutes CRBN AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human CRBN
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Isotype
- IgG
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Indications d'application
- FCM(1:20-100)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at 4°C
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Date de péremption
- 12 months
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- CRBN (Cereblon (CRBN))
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Autre désignation
- CRBN
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Sujet
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CRBN is a 442 amino acid protein which is highly concentrated in human brain tissue. CRBN functions are thought to be related to energy metabolism, learning and memory. Localized to the cytoplasm, CRBN acts as a protease in mitochondria and is thought to regulate the assembly of KCNT1, as well as the surface expression of KCNT1 in brain regions known to affect memory and learning, such as the hippocampus. The gene encoding CRBN belongs to a family of ATP-dependent lon proteases that play a role in membrane trafficking and proteolysis. Defects in the CRBN gene are associated with mild mental retardation.
Synonyms: Cereblon, DKFZp781K0715, MGC27358, MRT2A, OTTHUMP00000209555, piL, Protein cereblon, Protein x 0001, 2610203G15Rik, 2900045O07Rik, AF229032, AW108261, CRBN_HUMAN.
Antigène
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