PD-1 anticorps (FITC)
Aperçu rapide pour PD-1 anticorps (FITC) (ABIN2567415)
Antigène
Voir toutes PD-1 (PDCD1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- The MIH4 monoclonal antibody specifically reacts with human Programmed death-1 (PD-1 or CD279), a 50-55 kDA glycoprotein.
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Purification
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Isotype
- IgG1 kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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Stock
- 4 °C
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Stockage commentaire
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
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- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
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Autre désignation
- CD279
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Sujet
- The MIH4 monoclonal antibody specifically reacts with human Programmed death-1 (PD-1 or CD279), a 50-55 kDA glycoprotein. It is expressed on mainly on activated B, T, and myeloid cells. Within the cytoplasmic region, PD-1 contains an Immunoreceptor tyrosine-based inhibitory motif (ITIM) and seems to regulate peripheral tolerance. The lack or mutation of CD279 is linked to autoimmune disorders.
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ID gène
- 5133
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UniProt
- Q15116
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Pathways
- Cancer Immune Checkpoints
Antigène
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