L’anticorps anti-CD90.2 / Thy-1.2 Monoclonal produit chez le Rat a été validé pour FACS. Il convient pour la détection de CD90.2 / Thy-1.2 dans des échantillons provenant de Souris.
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Antigène
CD90.2 / Thy-1.2
Autre désignation
CD90.2
Sujet
The 30-H12 monoclonal antibody specifically binds to MouseCD90.2, an alloantigen known as Thy-1.2, expressed on thymocytes, mature T cells, epithelial cells, neurons, hematopoietic stem cells, and fibroblasts. CD90 is a membrane glycoprotein that regulates the adhesion and signal transduction in T lymphocytes, and the adhesion of thymocytes to thymic stroma. The interaction between 30-H12 and the antibody to the CD3/TCR complex upregulates thymocytes signal transduction and apoptosis and downregulates mature T cell proliferation. The 30-H12 antibody seems to be unable to cross-link with CD90.1.