Interleukin 17a anticorps (PE)
Aperçu rapide pour Interleukin 17a anticorps (PE) (ABIN2568240)
Antigène
Voir toutes Interleukin 17a (IL17A) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Specificité
- The 17B7 monoclonal antibody specifically binds to mouse and rat IL-17A, a pro-inflammatory cytokine.
-
Purification
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
-
Isotype
- IgG2a kappa
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.5 mg/mL
-
Buffer
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
-
Stock
- 4 °C
-
Stockage commentaire
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
-
-
- Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
-
Autre désignation
- IL-17A
-
Sujet
- The 17B7 monoclonal antibody specifically binds to mouse and rat IL-17A, a pro-inflammatory cytokine. It is produced by T helper 17 (Th17) cells, a unique subset of IL-23 dependent CD4+ T cells. Interleukin-17A is highly expressed in transplant rejection, asthma, psoriasis, and multiple sclerosis, and enhances the expression of ICAM-1 in human fibroblasts. The homodimer is expressed by activated peripheral CD4+ T lymphocytes. The Interleukin-17A binds to the IL-17 receptors (IL-17R) expressed by mast cells, monocytes and macrophages, fibroblasts, and endothelial and epithelial cells.
-
ID gène
- 16171, 301289
-
UniProt
- Q62386, Q61453
Antigène
-