MER/SKY (pTyr681), (pTyr749) anticorps

N° du produit ABIN2568354

L’anticorps anti-MER/SKY Polyclonal Lapin est utilisé pour la détection de MER/SKY dans des échantillons de Humain, Souris et Rat. Il a été validé pour IHC et WB.

Aperçu rapide pour MER/SKY (pTyr681), (pTyr749) anticorps (ABIN2568354)

Antigène: MER/SKY

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Détail du produit

Épitope: pTyr681, pTyr749

Specificité: The antibody detects endogenous levels of MER/SKY only when phosphorylated at tyrosine 749/681.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogène: MER/SKY (phospho Tyr749/681) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 749/681 (K-I-Y (p)-S-G) derived from Human MER/SKY .

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store antibody at -20°C for up to one year.

Détail du antigène

Antigène: MER/SKY

Sujet: This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

Poids moléculaire: 97 kDa

ID gène: 10461, 7301

NCBI Accession: NP_006334

UniProt: Q12866, Q06418