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RSK1/2/3/4 (pSer221), (pSer227), (Ser218), (Ser232) anticorps

Cet anticorps anti- est un anticorps Lapin Polyclonal détectant dans WB. Adapté pour Humain et Souris.
N° du produit ABIN2568448

Aperçu rapide pour RSK1/2/3/4 (pSer221), (pSer227), (Ser218), (Ser232) anticorps (ABIN2568448)

Antigène

RSK1/2/3/4

Reactivité

Humain, Souris

Hôte

  • 13
Lapin

Clonalité

  • 13
Polyclonal

Conjugué

  • 6
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Inconjugué

Application

  • 6
  • 6
Western Blotting (WB)
  • Épitope

    • 9
    • 9
    • 9
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer221, pSer227, Ser218, Ser232

    Specificité

    The antibody detects endogenous levels of RSK1/2/3/4 only when phosphorylated at serine 221/227/218/232.

    Purification

    Antibodies were purified by affinity-chromatography using epitope-specific peptide.

    Immunogène

    RSK1/2/3/4 (phospho Ser221/227/S218/232) antibody was raised against a peptide sequence around phosphorylation site of Serine 221/227/218/232 (A-Y-S (p)-F-C) derived from Human RSK1/2/3/4.

    Isotype

    IgG
  • Indications d'application

    Western Blot: 1:500~1:1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Store antibody at -20°C for up to one year.
  • Antigène

    RSK1/2/3/4

    Sujet

    This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway.

    Poids moléculaire

    85 kDa

    ID gène

    6195, 6197, 6196

    NCBI Accession

    NP_002944

    UniProt

    Q15418, P51812, Q15349, Q9UK32
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